NCAA Men's Tournament Sweet 16 Showdowns, Wagering Lines, Predictions, and Revised 2025 Odds for March Madness
The 2025 NCAA Men's Tournament rolls on with the Sweet 16 games, set to begin next weekend following the conclusion of Sunday's Round of 32 matchups. Few surprises have arisen thus far in the tournament, with betting favorites dominating. The NCAA Tournament has seen one bettor still alive with a $500,000 bet on Duke (+350) to cut down the nets and win the national championship, returning over $2 million if Duke emerges victorious.
The NCAA Tournament So Far
Thursday and Friday's March Madness games saw a few upsets, but betting favorites overall went 25-7 straight up and 19-13 against the spread (ATS), amounting to 59% betting winners. Game totals saw less scoring, with over/unders going 11-21, or 65% winners betting under the total.
Saturday's Round of 32 games saw favorites go 5-3 SU and 4-4 ATS, while over/under totals were 5-3. The Big Ten Conference held strong until Wisconsin and UCLA lost later games, dropping them to a 10-2 SU and ATS record heading into Sunday. Michigan State, Maryland, Illinois, and Oregon are trying to advance to the Sweet Sixteen.
Sunday's games will feature No. 1 seed Florida (-8.5) against 2-time defending champion Connecticut in the West Region, and No. 1 Duke (-11.5) against Baylor in the East.
FBI Warning Issued as Chinese Attack Sweeps iPhone and Android Users
Google Pixel's Unrivaled Upgrade Leaves Other Phones in the Dust
Google Confirms Gmail Upgrade: 3 Billion Users Must Now Make a Decision
As for the Sweet 16 matchups, Auburn and Houston won Saturday, with the Houston Cougars advancing to their sixth straight Sweet 16, while Gonzaga's streak of nine Sweet 16 appearances came to an end.
Updated Bracket, Schedules, and Scores
The Southeastern Conference (SEC) had a record 14 teams in the 2025 NCAA Tournament, and seven remain with top seeds No. 1 Florida, No. 2 Alabama, No. 3 Kentucky, and No. 6 Ole Miss still playing ahead of the Sweet 16.
Sweet 16 Matchups, Odds, TV Schedule
The following is a list of Sweet 16 games, along with their odds and TV schedule courtesy of FanDuel Sportsbook. All times are Eastern and will be updated as more information becomes available.
Thursday, March 27
East - Prudential Center (Newark, NJ)
- No. 1 Duke vs. Arizona/Oregon winner | Total | 7:40 p.m. |
- No. 6 BYU vs. No. 2 Alabama/No. 7 St. Mary's | Total | 10:10 p.m. |
West - Chase Center (San Francisco, CA)
- No. 10 Arkansas vs. No. 3 Texas Tech (-5.5) | Total 147.5 | 9:40 p.m. |
- No. 1 Florida vs. Maryland/No. 12 Colorado State | Total | 7:10 p.m. |
Friday, March 28
South - State Farm Arena (Atlanta, GA)
- No. 5 Michigan vs. No. 1 Auburn (-7.5) | Total 153.5 | 9:40 p.m. |
- No. 3 Iowa State/No. 6 Ole Miss vs. No. 2 Michigan State/No. 7 New Mexico | Total | 7:10 p.m. |
Midwest - Lucas Oil Stadium, (Indianapolis, IN)
- No. 4 Purdue vs. No. 1 Houston (-7.5) | Total 132.5 | 7:40 p.m. |
- No. 3 Kentucky vs. 2 Tennessee | Total | 10:10 p.m. |
Adjusted Odds to Win 2025 NCAA Tournament
College basketball odds and futures from FanDuel Sportsbook are subject to change. Here are the adjusted odds to win the national championship based on advanced statistics metrics of adjusted offensive and defensive efficiency.
- Duke (No. 3 offense, No. 4 defense): +225
- Florida (No. 1 offense, No. 10 defense): +350
- Auburn (No. 2 offense, No. 12 defense): +490
- Houston (No. 10 offense, No. 1 defense): +500
- Tennessee (No. 17 offense, No. 2 defense): +1600
- Iowa State (No. 20 offense, No. 8 defense): +2600
- Alabama: +2000
- Texas Tech (No. 5 offense, No. 37 defense): +2000
- Michigan State: +3200
- Maryland: +4600
- Arizona: +4800
- Purdue: +6500
- Michigan (No. 39 offense, No. 13 defense - was 150/1 prior to second round): +7000
- Arkansas (No. 66 offense, No. 18 defense - was 200/1 prior to second round): +9500
- BYU (No. 8 offense, No. 72 defense): +9500
- Kentucky: +10000
- Ole Miss: +15000
- St. Mary's: +16000
- Oregon: +60000
- Colorado State: +65000
- New Mexico: +130000
Duke and Florida have been the frontrunners in offensive efficiency, with Duke edging out Florida since both teams' opening games.
Sweet 16 Betting Trends and Notes
Several trends and notes are useful to consider when betting on the Sweet 16 round.
- Favorites: Superior-seeded teams have historically had success against the spread, but they have seen mixed results in recent years.
- Association Performance: The SEC has a strong record of success in the Sweet 16, going 23-14-2 ATS since 2003, which favors SEC teams like Alabama and Auburn.
- Double-Digit Seeds: Double-digit seeds have shown potential in recent tournaments, covering more than 60% of the time as underdogs.
- Lower-Seeded Teams: Lower-seeded teams have generally performed well ATS in recent tournaments.
- Total Trends: Games with totals under 138 have leaned towards Under 75% of the time in the Sweet 16, and favorites of eight points or more tend to see unders.
More in-depth analysis, predictions, and picks will be available as the Sweet 16 unfolds. Keep in mind that the odds and trends provided are subject to change based on the outcomes of games.
You can bet on it.
In the NCAA Tournament, the Sweet 16 matchups will be hosted at multiple venues, with Duke, Florida, Alabama, and Kentucky still representing the Southeastern Conference (SEC). FanDuel Sportsbook offers odds for these games, with Duke listed at +225 to win the national championship. Betting on Sweet 16 games should consider trends, such as the historic success of superior-seeded teams against the spread and the SEC's strong Sweet 16 record of 23-14-2 ATS since 2003.
One notable bettor has managed to stay in the tournament with a $500,000 bet on Duke to win the national championship, which would return over $2 million if Duke emerges victorious. As for the futures market, one bettor still has a $13000 stake on Duke to win it all.
The Sweet 16 sees several teams attempting to advance, including Michigan State, Michigan, and Maryland from the Big Ten Conference, Oregon, and Auburn. Odds for these teams range from +350 for Florida to +160000 for New Mexico. Keep in mind that the odds may change based on the outcomes of the games.
